隨著RNA替代RNA處理，調節RNA和RNA介導的酶促機制等現象對細胞中基因表達調控的重要性的出現，以及RNA對疾病發病機制和正常發育的貢獻的認識，已經成為了解所有生命科學學科必不可少的RNA生物學領域。 WIREs RNA的目標是為這個有趣且不斷發展的領域提供全面，最新和連貫的報道，為RNA專家和跨學科研究人員提供框架，不僅可以獲得RNA生物學領域的觀點，而且可以產生新的見解和應用程序。主要議題包括：RNA結構和動力學; RNA進化和基因組學;基于RNA的催化; RNA與蛋白質和其他分子的相互作用;翻譯; RNA加工; RNA出口/本地化; RNA轉換和監測;調節RNA / RNAi /核糖開關;疾病與發展中的RNA;和RNA方法。

The emergence of the importance of such phenomena as alternative RNA processing, regulatory RNAs, and RNA-mediated enzymatic mechanisms to the regulation of gene expression in cells, along with the recognition of the contributions of RNA to disease pathogenesis and normal development, have made an understanding of the field of RNA biology essential to all life science disciplines. It is the goal of WIREs RNA to provide comprehensive, up-to-date, and coherent coverage of this interesting and growing field, providing a framework for both RNA experts and interdisciplinary researchers to not only gain perspective in areas of RNA biology, but to generate new insights and applications as well. Major topics to be covered are: RNA Structure and Dynamics; RNA Evolution and Genomics; RNA-Based Catalysis; RNA Interactions with Proteins and Other Molecules; Translation; RNA Processing; RNA Export/Localization; RNA Turnover and Surveillance; Regulatory RNAs/RNAi/Riboswitches; RNA in Disease and Development; and RNA Methods.