移植感染性疾病已被建立為一個論壇,介紹最新的信息,預防和治療感染復雜的器官和骨髓移植。期刊的觀點是,感染和同種異體移植排斥(或移植物抗宿主病)緊密交織在一起,而且一個領域的進展將對另一個領域產生直接影響。移植受體與潛在微生物侵略者的相互作用,免疫抑制策略對這種相互作用的影響,以及在感染、排斥或移植物抗宿主病過程中釋放的細胞因子、生長因子和趨化因子的影響,是本雜志的興趣和任務的中心。移植傳染病旨在向骨髓、腎臟、肝臟、心臟、肺、腸道和胰腺移植的臨床醫生和科學家傳播與移植傳染病并發癥有關的最新信息。從新型免疫抑制劑到異種移植,傳染病的后果和對創新移植策略的關注是本雜志非常關注的問題。此外,本雜志還特別有責任告知社區的初級保健醫師,他們越來越多地分擔照顧這些患者的責任,以及關于預防和治療移植受者感染的特殊考慮。以國際編輯委員會為例,全世界都在尋找既涉及一般問題又涉及更受限制的地理進口問題的文章。移植性傳染病包括有關重要學科的最新綜述文章、臨床調查結果、有趣的病例報告和兩個復發特征:臨床病理會議和移植感染性疾病的基礎科學評論。涉及的主題包括特定感染、重要感染的流行病學、免疫抑制和感染暴露之間的相互作用、特定感染的診斷、發病機制和臨床管理。基礎科學和臨床文章都有特色。如果存在爭議,問題的雙方都會被提出。本雜志旨在滿足所有參與器官和骨髓移植受者研究和護理的臨床醫生和科學家的需求。
Transplant Infectious Disease has been established as a forum for presenting the most current information on the prevention and treatment of infection complicating organ and bone marrow transplantation. The point of view of the journal is that infection and allograft rejection (or graft-versus-host disease) are closely intertwined, and that advances in one area will have immediate consequences on the other. The interaction of the transplant recipient with potential microbial invaders, the impact of immunosuppressive strategies on this interaction, and the effects of cytokines, growth factors, and chemokines liberated during the course of infections, rejection, or graft-versus-host disease are central to the interests and mission of this journal.Transplant Infectious Disease is aimed at disseminating the latest information relevant to the infectious disease complications of transplantation to clinicians and scientists involved in bone marrow, kidney, liver, heart, lung, intestinal, and pancreatic transplantation. The infectious disease consequences and concerns regarding innovative transplant strategies, from novel immunosuppressive agents to xenotransplantation, are very much a concern of this journal. In addition, this journal feels a particular responsibility to inform primary care practitioners in the community, who increasingly are sharing the responsibility for the care of these patients, of the special considerations regarding the prevention and treatment of infection in transplant recipients. As exemplified by the international editorial board, articles are sought throughout the world that address both general issues and those of a more restricted geographic import.Transplant Infectious Disease includes state-of-the-art review articles on important subjects, the results of clinical investigation, interesting case reports, and two recurring features: a clinical-pathologic conference and reviews of the basic science foundation of transplant infectious disease. Subjects covered include specific infections, the epidemiology of important infections, the interaction among immunosuppression and infection exposure, the diagnosis of specific infection, pathogenesis, and clinical management. Both basic science and clinical articles are featured. Where controversy exists, both sides of an issue are presented. This journal is meant to serve the needs of all clinicians and scientists involved in the study and care of organ and bone marrow transplant recipients.
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