該雜志旨在通過發表有關統計和其他定量方法的論文來影響醫學及其相關科學的實踐。論文將解釋新的方法，并展示其應用，最好是通過一個實質性的、真實的、激勵性的例子或基于一個說明性實例的綜合評價。另外，論文還將報告案例研究，其中對既定方法的創造性使用或技術概括是針對實質性應用的。此外，還將出版有關統計應用于醫學的一般主題的評論和教程。出版的主要標準是統計方法對特定醫學問題的適用性和闡述的清晰度。主要包含數學內容的論文將被排除在外。該雜志旨在加強統計學家、臨床醫生和醫學研究人員之間的交流。

The journal aims to influence practice in medicine and its associated sciences through the publication of papers on statistical and other quantitative methods. Papers will explain new methods and demonstrate their application, preferably through a substantive, real, motivating example or a comprehensive evaluation based on an illustrative example. Alternatively, papers will report on case-studies where creative use or technical generalizations of established methodology is directed towards a substantive application. Reviews of, and tutorials on, general topics relevant to the application of statistics to medicine will also be published. The main criteria for publication are appropriateness of the statistical methods to a particular medical problem and clarity of exposition. Papers with primarily mathematical content will be excluded. The journal aims to enhance communication between statisticians, clinicians and medical researchers.