《生殖毒理學(xué)》借鑒眾多學(xué)科,及時發(fā)表了有關(guān)化學(xué)和物理因素對生殖影響的原始研究成果。該雜志由產(chǎn)科醫(yī)生、兒科醫(yī)生、胚胎學(xué)家、畸形學(xué)家、遺傳學(xué)家、毒物學(xué)家、雄激素學(xué)家以及其他對檢測潛在生殖危害感興趣的人撰寫,是研究人員和從業(yè)者交流的平臺。文章重點介紹了體外、動物和臨床研究在臨床醫(yī)學(xué)實踐中的應(yīng)用。生殖的各個方面都在生殖毒理學(xué)的范圍內(nèi),包括雄性和雌性配子的形成和成熟、性功能、配子融合周圍的事件和受精卵的發(fā)育、生殖道內(nèi)受精卵的營養(yǎng)和運輸、植入、胚胎發(fā)生、生殖道內(nèi)受精卵的營養(yǎng)和運輸。宮內(nèi)生長、胎盤形成和胎盤功能、分娩、哺乳和新生兒存活。男性的生殖不良反應(yīng)與女性的生殖不良反應(yīng)一樣重要。為了提供一個平衡的方法介紹,將同等重視臨床和動物或體外工作。貢獻者將研究的典型終點包括不孕、性功能障礙、自然流產(chǎn)、畸形、異常組織發(fā)生、死胎、宮內(nèi)生長遲緩、早產(chǎn)、行為異常和圍產(chǎn)兒死亡率。除了最初的研究文章外,生殖毒理學(xué)還發(fā)表解釋性評論文章、社論、書信、書評和會議公告。這本雜志每期的第一部分都是對特定化學(xué)或物理因素對生殖影響的研究進行深入、及時的回顧。建議潛在作者在提交此類評論前與總編輯聯(lián)系。
Drawing from a large number of disciplines, Reproductive Toxicology publishes timely, original research on the influence of chemical and physical agents on reproduction. Written by and for obstetricians, pediatricians, embryologists, teratologists, geneticists, toxicologists, andrologists, and others interested in detecting potential reproductive hazards, the journal is a forum for communication among researchers and practitioners. Articles focus on the application of in vitro, animal and clinical research to the practice of clinical medicine. All aspects of reproduction are within the scope of Reproductive Toxicology, including the formation and maturation of male and female gametes, sexual function, the events surrounding the fusion of gametes and the development of the fertilized ovum, nourishment and transport of the conceptus within the genital tract, implantation, embryogenesis, intrauterine growth, placentation and placental function, parturition, lactation and neonatal survival. Adverse reproductive effects in males will be considered as significant as adverse effects occurring in females. To provide a balanced presentation of approaches, equal emphasis will be given to clinical and animal or in vitro work. Typical end points that will be studied by contributors include infertility, sexual dysfunction, spontaneous abortion, malformations, abnormal histogenesis, stillbirth, intrauterine growth retardation, prematurity, behavioral abnormalities, and perinatal mortality. In addition to original research articles, Reproductive Toxicology also publishes interpretative review articles, editorials, letters, book reviews, and conference announcements. The first section of each issue of the journal is devoted to an in-depth, timely review of research on the effect of particular chemical or physical agents on reproduction. Potential authors are encouraged to contact the Editor-in-Chief before submitting such a review.
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