突變研究綜述的主題領(lǐng)域包括突變研究及其應(yīng)用的整個(gè)科學(xué)領(lǐng)域，特別強(qiáng)調(diào)突變與疾病的關(guān)系。因此，本節(jié)將介紹人類基因組研究的進(jìn)展（包括變異檢測和功能基因組學(xué)的進(jìn)化技術(shù)），以及在臨床遺傳學(xué)、基因治療和相關(guān)環(huán)境因素健康風(fēng)險(xiǎn)評估中的應(yīng)用。遺傳毒理學(xué)和環(huán)境誘變（包括調(diào)節(jié)環(huán)境因子遺傳活性的因子）將繼續(xù)成為本節(jié)的重點(diǎn)。除了完整的評論外，還將發(fā)布關(guān)于特定主題的小評論。

The subject areas of Reviews in Mutation Researchencompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus this section will cover advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concern. Genetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section. In addition to full-length reviews, mini-reviews on specific topical themes will be published.