該雜志的目的是推進在多尺度計算科學和工程的不同領域的研究和實踐。該雜志將向該領域發表具有普遍價值的原創論文和教育性文章，以彌合基于多尺度原則的產品建模、仿真和設計之間的差距。該雜志的范圍包括與物理尺度橋接有關的論文，從原子級到全尺度產品，以及涉及多個物理過程在多個時空尺度上相互作用的問題。計算納米技術、計算生物技術和計算能源科學的新興領域受到該雜志的特別關注。該雜志旨在引起學術界、政府界和工業界的研究人員和從業人員的興趣和使用。

The aim of the journal is to advance the research and practice in diverse areas of Multiscale Computational Science and Engineering. The journal will publish original papers and educational articles of general value to the field that will bridge the gap between modeling, simulation and design of products based on multiscale principles. The scope of the journal includes papers concerned with bridging of physical scales, ranging from the atomic level to full scale products and problems involving multiple physical processes interacting at multiple spatial and temporal scales. The emerging areas of computational nanotechnology and computational biotechnology and computational energy sciences are of particular interest to the journal. The journal is intended to be of interest and use to researchers and practitioners in academic, governmental and industrial communities.