基因組研究(Genome Research)成立于1995年,是一份國(guó)際性的、連續(xù)出版的、同行評(píng)議的期刊,發(fā)表關(guān)于所有生物體基因組的結(jié)構(gòu)、功能、生物學(xué)和進(jìn)化的研究,長(zhǎng)期以來(lái)一直強(qiáng)調(diào)基因組規(guī)模分析、染色質(zhì)結(jié)構(gòu)和功能、表觀基因組學(xué)、系統(tǒng)遺傳學(xué)和蛋白質(zhì)組學(xué)。我們還以基因發(fā)現(xiàn)為特色,為高通量的實(shí)驗(yàn)和計(jì)算方法提供新的見(jiàn)解和報(bào)告。除這些核心領(lǐng)域外,《日刊》現(xiàn)在對(duì)下列領(lǐng)域特別感興趣:基因組序列變異的綜合表征理解表型復(fù)雜性的基礎(chǔ)網(wǎng)絡(luò)生物學(xué)與遺傳變異的功能效應(yīng)物種起源、適應(yīng)和基因組多樣性的進(jìn)化機(jī)制,包括對(duì)古代DNA的研究基因組醫(yī)學(xué),包括外顯率、表達(dá)和修飾效應(yīng)的機(jī)制通過(guò)單細(xì)胞分析了解基因組和生物學(xué)過(guò)程提供深入了解生物過(guò)程的新型計(jì)算算法基因組編輯與工程
Launched in 1995, Genome Research is an international, continuously published, peer-reviewed journal that publishes studies on the structure, function, biology, and evolution of genomes of all organisms, with a long-standing emphasis on genome-scale analyses, chromatin structure and function, epigenomics, systems genetics, and proteomics. We also feature gene discoveries that provide novel insights and reports of high-throughput experimental and computational approaches. In addition to these core areas, the journal is now particularly interested in the following areas:comprehensive characterization of genome sequence variationunderstanding the basis of phenotypic complexitynetwork biology and the functional effects of genetic variationevolutionary mechanisms of species origin, adaptation, and genomic diversity, including the study of ancient DNAgenomic medicine, including mechanisms of penetrance, expressivity, and modifier effectsunderstanding genomic and biological processes through single-cell analysesnovel computational algorithms that provide insight into biological processesgenome editing and engineering
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