BBA生物能學(xué)涵蓋了涉及能量轉(zhuǎn)移和轉(zhuǎn)換的生物膜領(lǐng)域。特別關(guān)注x射線(xiàn)晶體學(xué)等方法獲得的結(jié)構(gòu),以及光合作用、線(xiàn)粒體和細(xì)菌呼吸、氧化磷酸化、運(yùn)動(dòng)性和轉(zhuǎn)運(yùn)等成分的分子機(jī)制。它涵蓋了結(jié)構(gòu)生物學(xué)、分子模型、光譜學(xué)和生物物理學(xué)在這些系統(tǒng)中的應(yīng)用,通過(guò)線(xiàn)粒體生物學(xué)的生物能量方面,包括生物醫(yī)學(xué)方面的能量代謝在線(xiàn)粒體疾病、神經(jīng)退行性疾病,如帕金森和阿爾茨海默氏癥、衰老、糖尿病甚至癌癥中的應(yīng)用。
BBA Bioenergetics covers the area of biological membranes involved in energy transfer and conversion. In particular, it focuses on the structures obtained by X-ray crystallography and other approaches, and molecular mechanisms of the components of photosynthesis, mitochondrial and bacterial respiration, oxidative phosphorylation, motility and transport. It spans applications of structural biology, molecular modeling, spectroscopy and biophysics in these systems, through bioenergetic aspects of mitochondrial biology including biomedicine aspects of energy metabolism in mitochondrial disorders, neurodegenerative diseases like Parkinson's and Alzheimer's, aging, diabetes and even cancer.
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